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The amount of synephrine and caffeine used in PhysiqueSeries Fat Burner has been clinically found to be effective without side effects . Salicin supplementation has been found to potentiate the thermogenic effects of synephrine in dieting individuals . slim-now-keto This is effect is via salicylic acid’s ability to reduce dampening signals in the body which increasingly limit synephrine’s thermogenesis stimulating mechanism . While caffeine alone is good, more research has found extremely beneficial relationships between caffeine and other ingredients found in PhysiqueSeries for increasing fat metabolism .